[See Dr Oz, Antidepressant Serotonin Imbalance, Suicide Warning, Depression, here]
[See. CDC Vital Signs. “Prescription Painkiller Overdoses: A growing epidemic, especially among women,” saying opioid deaths are as “under-recognized problem, here.]
In my search I found studies suggesting that antidepressants aren't treating clinical depression effectively, if at all. Other information suggests that antidepressants are treating the depression angle of chronic pain, but even in these studies, they were considering people with MAJOR depression, a clinical psychiatric condition. We need research on psychoactive drugs that are NOT conducted by pharmaceutical companies.
You might be interested in reading the PAINS/Project Environmental Scan, Chronic Pain Management and the Practical Implications of Addressing Recommendations Put Forth in the Institute of Medicine (IOM) Report, Relieving Pain in America, here.